Mesothelial cell CSF1 sustains peritoneal macrophage proliferation
نویسندگان
چکیده
منابع مشابه
Hydralazine inhibits human peritoneal mesothelial cell proliferation and collagen synthesis.
The integrity of the mesothelial layer is essential for both defence and solute transport in continuous ambulatory peritoneal dialysis (CAPD). The human peritoneal mesothelial cell (HPMC) culture has been shown to be a very useful tool to study the peritoneal mesothelial stem cell behaviour. We investigated whether hydralazine, an antihypertensive agent frequently used, might affect HPMC growth...
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Obesity causes dramatic proinflammatory changes in the adipose tissue immune environment, but relatively little is known regarding how this inflammation responds to weight loss (WL). To understand the mechanisms by which meta-inflammation resolves during WL, we examined adipose tissue leukocytes in mice after withdrawal of a high-fat diet. After 8 weeks of WL, mice achieved similar weights and ...
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Fedarko, N.S., Jain, A., Karadag, A., Van Eman, M.R. & Fisher, L.W. (2001) Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clinical Cancer Research, 7, 4060– 4066. Flamant, S., Kortulewski, T., Dugray, A., Bonnet, M.L., Guillier, M., Guilhot, F., Bourhis, J.H., Vainchenker, W., Roux, D.T.L. & Turhan, A.G. (2005) Osteopontin is upregulated by BCR-ABL...
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OBJECTIVE This study reviews evidence that implicates high glucose (HG) in the pathogenesis of peritoneal fibrosis and proposes mechanisms potentially involved in the HG-induced peritoneal fibrosis that is observed in long-term peritoneal dialysis (PD) patients. DESIGN Selected Western literature is reviewed, examining the effect of HG on rat or human peritoneal mesothelial cell (HPMC) biolog...
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BACKGROUND/AIMS Peritoneal fibrosis is a frequent complication of peritoneal dialysis that follows inflammation. It is recognized that epithelial-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs), plays a key role in fibrogenesis. However, the relationship between inflammatory macrophages and PMCs remains elusive. In this study, we investigated the effects of different polariz...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2019
ISSN: 0014-2980,1521-4141
DOI: 10.1002/eji.201948164